Scientific Advisory Board

Stephen Goff, Ph.D,

Dr. Goff has been the Higgins Professor in the Departments of Biochemistry and Microbiology at Columbia University Medical Center since June 1990. He is a fellow of the Howard Hughes Medical Institute, a member of the National Academy of Sciences, and a member of the National Academy of Medical Sciences. He received an A.B. in biophysics from Amherst College and a Ph.D. in biochemistry from Stanford University. Dr. Goff performed post-doctoral research at the Massachusetts Institute of Technology in the laboratory of Dr. David Baltimore. He has published over 250 scientific articles, including the first descriptions of clones for the v-abl oncogene and c-abl protooncogene; two important findings which contributed to the development of the antitumor drug Gleevec.

Richard Granstein, M.D.

Richard Granstein received his B.S. from MIT, his M.D. at the UCLA School of Medicine, and did his residency in dermatology at Massachusetts General Hospital. In 1984 he became a faculty member of the Harvard Medical School and the Massachusetts General Hospital. Since 1995, he has been the George W. Hambrick, Jr. Professor and Chairman of Dermatology at Cornell-Weill Medical Center in New York City and Dermatologist-in- Chief at the New York Weill-Cornell Medical Center of New York Presbyterian Hospital, with a specialty in dendritic cells, an important branch of innate immunity.

Beatrice Uziely, MD

Dr. Uziely is the Head, Oncology Ambulatory Services, Hadassah Hospital where she is a leading breast cancer specialist. Access to a large number of breast cancer patients, and patients with recurrent breast cancer undergoing Herceptin therapy, position her as an excellent resource for the Company in our breast cancer clinical trials. Dr. Uziely has authored over seventy medical publications, approximately half of which relate to the treatment of recurrent breast cancer. She is a founder of Incure Ltd, a Company with interests in mechanisms of breast cancer invasion and breast cancer diagnostics.

Wayne Yokoyama, MD

Wayne Yokoyama is a Howard Hughes Medical Institute Investigator, and Professor and Chief of Rheumatology at Washington University School of Medicine, where he specializes in innate immunity. Among his awards is the Novartis 2001 Prize for Basic Immunology given every three years to the most prestigious work in the field.